UBE4B 抗体 (N-Term)
Quick Overview for UBE4B 抗体 (N-Term) (ABIN2785770)
抗原
See all UBE4B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SPMFCSVASF GASSLSSLYE SSPAPTPSFW SSVPVMGPSL ASPSRAASQL
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预测反应
- Dog: 79%, Human: 100%, Pig: 79%
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产品特性
- This is a rabbit polyclonal antibody against UBE4B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE4B
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anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (C-Term) antibody
UBE4B 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (AA 112-142), (N-Term) antibodyUBE4B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4133 unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) antibodyUBE4B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (AA 1075-1173) antibodyUBE4B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (AA 869-1179) antibodyUBE4B 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (AA 1075-1173) antibodyUBE4B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D5 unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (N-Term) antibodyUBE4B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (AA 254-303) antibodyUBE4B 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) (AA 130-250) antibodyUBE4B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Conjugation Factor E4 B (UBE4B) antibodyUBE4B 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1302 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))
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别名
- UBE4B
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背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: E4, HDNB1, KIAA0684, UBOX3, UFD2, UFD2A
Protein Interaction Partner: TRIP12, UBC, FBXW11, HGS, STAM, TP53, MDM2, NUSAP1, NUDCD3, RBM12, PDE3A, CDKN2A, UBL7, UBE2D3, CDC27, TTK, IGBP1, HDLBP, TTC9C, MRPL53, ZFYVE19, SARNP, SRPRB, VPS35, UBA6, VPS29, UFM1, SBDS, VPS36, UBQLN1, UBXN7, UBE2C, AHCYL1, SSSCA1, SF3B4, PPIF, SCO2,
Protein Size: 1302 -
分子量
- 146 kDa
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基因ID
- 10277
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NCBI登录号
- NM_001105562, NP_001099032
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UniProt
- O95155
抗原
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