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LCK 抗体 (N-Term)

Name: LCK 抗体 (N-Term)
SKU: ABIN2785755
Availability: OutOfStock

This anti-LCK antibody is a 兔多克隆 antibody detecting LCK in WB. Suitable for 人, 小鼠, 大鼠, Cow, 绵羊, 兔, 犬, 马和豚鼠.

WB Suggested Anti-LCK Antibody Titration: 0. (LCK 抗体 (N-Term))

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产品编号 ABIN2785755

发货至: 中国

Quick Overview for LCK 抗体 (N-Term) (ABIN2785755)

抗原

See all LCK 抗体

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

适用

人, 小鼠, 大鼠, Cow, 绵羊, 兔, 犬, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This LCK antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product LCK Primary Antibody

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N-Term

序列

PSHDGDLGFE KGEQLRILEQ SGEWWKAQSL TTGQEGFIPF NFVAKANSLE

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%

产品特性

This is a rabbit polyclonal antibody against LCK. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human LCK
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 3F7-F5 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibody
LCK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibody
LCK 适用: 人 WB, IP, ICC, ICFC 宿主: 小鼠 Monoclonal LCK-01 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibody
LCK 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibody
LCK 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 39-52) antibody
Verified LCK 适用: 人, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 509 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

别名

LCK

背景

LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Alias Symbols: YT16, p56lck, pp58lck, LSK
Protein Interaction Partner: LZTS2, CDKAL1, BAG6, UBC, WASL, WAS, env, SMAD3, SMAD2, MAPK1, HSP90AA1, Mbp, HAVCR2, PTPN22, G3BP1, nef, LAT, KHDRBS1, ADAM15, ZAP70, PAK2, LCK, CBL, SOCS3, SOCS2, SOCS1, IL2RB, CISH, YWHAQ, AJUBA, CD5, CBLB, SKAP1, SYK, SOS1, CD38, CD247, CD3E, FAM174A,
Protein Size: 509

分子量

58 kDa

基因ID

3932

NCBI登录号

NM_001042771, NP_001036236

UniProt

P06239

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling