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LCK 抗体 (N-Term)

LCK 适用: 人, 小鼠, 大鼠, Cow, Pig, 绵羊, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785754
发货至: 中国
  • 抗原 See all LCK 抗体
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    抗原表位
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    N-Term
    适用
    • 157
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    人, 小鼠, 大鼠, Cow, Pig, 绵羊, 犬, 马, 兔, 豚鼠
    宿主
    • 141
    • 14
    • 2
    克隆类型
    • 143
    • 15
    多克隆
    标记
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    This LCK antibody is un-conjugated
    应用范围
    • 122
    • 86
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    Western Blotting (WB)
    序列
    ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against LCK. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human LCK
    Top Product
    Discover our top product LCK Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    别名
    LCK (LCK 产品)
    别名
    zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56 antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody
    背景
    LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
    Protein Interaction Partner: LZTS2, CDKAL1, BAG6, UBC, WASL, WAS, env, SMAD3, SMAD2, MAPK1, HSP90AA1, Mbp, HAVCR2, PTPN22, G3BP1, nef, LAT, KHDRBS1, ADAM15, ZAP70, PAK2, LCK, CBL, SOCS3, SOCS2, SOCS1, IL2RB, CISH, YWHAQ, AJUBA, CD5, CBLB, SKAP1, SYK, SOS1, CD38, CD247, CD3E, FAM174A,
    Protein Size: 363
    分子量
    39 kDa
    基因ID
    3932
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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