SH3KBP1 抗体 (N-Term)
Quick Overview for SH3KBP1 抗体 (N-Term) (ABIN2785720)
抗原
See all SH3KBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- TGMFPSNFIK ELSGESDELG ISQDEQLSKS SLRETTGSES DGGDSSSTKS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against SH3KBP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SH3KBP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 628 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))
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别名
- SH3KBP1
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背景
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This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Alias Symbols: CIN85, GIG10, MIG18, HSB1, HSB-1, CD2BP3
Protein Interaction Partner: PNMA5, ZBTB7B, SH3KBP1, STAP1, FRS3, SPRY2, ASAP2, PSMA3, CBL, UBC, RAF1, LOX, INPP5D, Dlg4, FAP, ARHGAP17, Ap2a1, Irf2bp1, Gcdh, Sept7, Wipf1, Chtf8, Cblb, Shkbp1, Rtkn2, Idh3b, Pik3ap1, Slc25a12, Wasl, Ap2b1, Arap1, Far1, Cltc, Timm50, Actn4, Sept6, Net
Protein Size: 628 -
分子量
- 68 kDa
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基因ID
- 30011
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NCBI登录号
- NM_001024666, NP_001019837
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UniProt
- Q5JPT5
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途径
- EGFR Signaling Pathway, EGFR Downregulation
抗原
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