HMBS 抗体 (Middle Region)
(1 reference)Quick Overview for HMBS 抗体 (Middle Region) (ABIN2785719)
抗原
See all HMBS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SSLRRAAQLQ RKFPHLEFRS IRGNLNTRLR KLDEQQEFSA IILATAGLQR
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预测反应
- Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against HMBS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HMBS
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anti-Hydroxymethylbilane Synthase (HMBS) (AA 283-330) antibody
HMBS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (AA 1-361) antibodyHMBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (AA 1-361) antibodyHMBS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E8 unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (AA 85-337) antibodyHMBS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (AA 160-173) antibodyVerified HMBS 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (Internal Region) antibodyHMBS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (AA 1-361) antibodyHMBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) antibodyHMBS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (AA 146-195) antibodyHMBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxymethylbilane Synthase (HMBS) (N-Term) antibodyHMBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 361 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Acute intermittent porphyria with peripheral neuropathy: a follow-up study after hematin treatment." in: Journal of the neurological sciences, Vol. 260, Issue 1-2, pp. 231-5, (2007) (PubMed).
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: "Acute intermittent porphyria with peripheral neuropathy: a follow-up study after hematin treatment." in: Journal of the neurological sciences, Vol. 260, Issue 1-2, pp. 231-5, (2007) (PubMed).
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- HMBS (Hydroxymethylbilane Synthase (HMBS))
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别名
- HMBS
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背景
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HMBS is a member of the hydroxymethylbilane synthase superfamily. It is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria.This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: PBG-D, PBGD, UPS, PORC
Protein Interaction Partner: RANBP9, APP, UBC,
Protein Size: 361 -
分子量
- 40 kDa
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基因ID
- 3145
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NCBI登录号
- NM_000190, NP_000181
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UniProt
- P08397
抗原
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