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GALE 抗体 (Middle Region)

GALE 适用: 人, 大鼠, 犬, Pig, 兔, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785691
发货至: 中国
  • 抗原 See all GALE 抗体
    GALE (UDP-Galactose-4-Epimerase (GALE))
    抗原表位
    • 15
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 33
    • 20
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 犬, Pig, 兔, Cow, 马
    宿主
    • 45
    • 3
    克隆类型
    • 47
    • 1
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GALE antibody is un-conjugated
    应用范围
    • 37
    • 15
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG
    预测反应
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against GALE. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human GALE
    Top Product
    Discover our top product GALE Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 348 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GALE (UDP-Galactose-4-Epimerase (GALE))
    别名
    GALE (GALE 产品)
    别名
    GALE antibody, im:7147391 antibody, wu:fb05f01 antibody, zgc:136578 antibody, F15H21.11 antibody, F15H21_11 antibody, REB1 antibody, ROOT EPIDERMAL BULGER1 antibody, ROOT HAIR DEFECTIVE 1 antibody, UDP-GLUCOSE 4-EPIMERASE antibody, UGE4 antibody, ECK0748 antibody, galD antibody, JW0742 antibody, SMU.888 antibody, BA5505 antibody, BA5700 antibody, VFA0352 antibody, galE antibody, 2310002A12Rik antibody, AI323962 antibody, 1n569 antibody, xgale antibody, SDR1E1 antibody, UDP-galactose-4-epimerase antibody, NAD(P)-binding Rossmann-fold superfamily protein antibody, UDP-galactose 4-epimerase GalE antibody, UDP-glucose 4-epimerase antibody, UDP-glucose 4-epimerase GalE antibody, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase antibody, galactose-4-epimerase, UDP antibody, UDP-galactose-4-epimerase L homeolog antibody, GALE antibody, gale antibody, RHD1 antibody, ECs0787 antibody, galE antibody, galE1 antibody, galE2 antibody, STY0809 antibody, galE-2 antibody, SG0897 antibody, galD antibody, Ent638_1250 antibody, Gale antibody, gale.L antibody
    背景
    GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
    Alias Symbols: SDR1E1
    Protein Interaction Partner: GALE, SUMO2, UBC, BAG3, FN1, APP,
    Protein Size: 348
    分子量
    38 kDa
    基因ID
    2582
    NCBI登录号
    NM_001008216, NP_001008217
    UniProt
    Q14376
    途径
    Response to Water Deprivation, Cellular Glucan Metabolic Process
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