GALE 抗体 (Middle Region)
Quick Overview for GALE 抗体 (Middle Region) (ABIN2785691)
抗原
See all GALE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against GALE. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GALE
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anti-UDP-Galactose-4-Epimerase (GALE) antibody
GALE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-340) antibodyGALE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 142-171) antibodyGALE 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21189 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 129-348) antibodyGALE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 201-250) antibodyGALE 适用: 人, 犬, Cow, Pig, 兔, 马, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (N-Term) antibodyGALE 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (N-Term) antibodyGALE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 348 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GALE (UDP-Galactose-4-Epimerase (GALE))
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别名
- GALE
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背景
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GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
Alias Symbols: SDR1E1
Protein Interaction Partner: GALE, SUMO2, UBC, BAG3, FN1, APP,
Protein Size: 348 -
分子量
- 38 kDa
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基因ID
- 2582
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NCBI登录号
- NM_001008216, NP_001008217
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UniProt
- Q14376
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途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
抗原
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