GALE 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for GALE 抗体 (N-Term) (ABIN2785690)
抗原
See all GALE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- AEKVLVTGGA GYIGSHTVLE LLEAGYLPVV IDNFHNAFRG GGSLPESLRR
-
预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 91%, Pig: 91%, Rabbit: 92%, Rat: 91%
-
产品特性
- This is a rabbit polyclonal antibody against GALE. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GALE
-
-
anti-UDP-Galactose-4-Epimerase (GALE) antibody
GALE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-340) antibodyGALE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) antibodyKD Validated GALE 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13050 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 142-171) antibodyGALE 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21189 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 129-348) antibodyGALE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT6G10 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 201-250) antibodyGALE 适用: 人, 犬, Cow, Pig, 兔, 马, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 348 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- GALE (UDP-Galactose-4-Epimerase (GALE))
-
别名
- GALE
-
背景
-
GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
Alias Symbols: SDR1E1
Protein Interaction Partner: GALE, SUMO2, UBC, BAG3, FN1, APP,
Protein Size: 348 -
分子量
- 38 kDa
-
基因ID
- 2582
-
NCBI登录号
- NM_001008216, NP_001008217
-
UniProt
- Q14376
-
途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
抗原
-
