IMPDH2 抗体 (C-Term)
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Quick Overview for IMPDH2 抗体 (C-Term) (ABIN2785674)
抗原
See all IMPDH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SCQDIGAKSL TQVRAMMYSG ELKFEKRTSS AQVEGGVHSL HSYEKRLF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against IMPDH2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human IMPDH2
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anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 1-514) antibody
IMPDH2 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 1E12-B6 unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 5-514) antibodyIMPDH2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyIMPDH2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyIMPDH2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyIMPDH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyKD Validated IMPDH2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB6135 unconjugated Recombinant Antibody
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 215-514) antibodyIMPDH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 215-514) antibodyIMPDH2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 215-514) antibodyIMPDH2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 1-514) antibodyIMPDH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 514 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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别名
- IMPDH2
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背景
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IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IMPD2, IMPDH-II
Protein Interaction Partner: RSG1, APIP, HUWE1, UBC, IMPDH2, CDK2, RPA1, RPA3, RPA2, PRKAR2A, IMPDH1, EIF2S3, PARK2, MAPK10, SOX2, NPM1, PEX14, FN1, RPLP0P6, RPS6, RPL15, FOLR1, FBXO6, GRB2, UBQLN4, PIAS4, COPS5, COPS6, CUL3, YWHAZ, FBXO25, SIRT7, HDAC5, MME, SUMO4, AKT1, IKBKE, ATG5
Protein Size: 514 -
分子量
- 56 kDa
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基因ID
- 3615
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NCBI登录号
- NM_000884, NP_000875
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UniProt
- P12268
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途径
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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