IMPDH1 抗体 (Middle Region)
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北京 101111
Quick Overview for IMPDH1 抗体 (Middle Region) (ABIN2785671)
抗原
See all IMPDH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- IMPDH1 Antibody - middle region
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序列
- KKGKLPIVND CDELVAIIAR TDLKKNRDYP LASKDSQKQL LCGAAVGTRE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against IMPDH1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human IMPDH1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54363-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
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别名
- IMPDH1
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背景
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Background Information: IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
Gene Name: IMP (inosine 5'-monophosphate) dehydrogenase 1
Alternative Symbols: IMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608
Protein Name: Inosine-5'-monophosphate dehydrogenase 1
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分子量
- 55 kDa
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基因ID
- 3614
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NCBI登录号
- NP_899066
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UniProt
- P20839
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途径
- Ribonucleoside Biosynthetic Process
抗原
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