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GAD 抗体 (N-Term)

This anti-GAD antibody is a 兔 多克隆 antibody detecting GAD in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔 和 马.
产品编号 ABIN2785666
发货至: 中国

Quick Overview for GAD 抗体 (N-Term) (ABIN2785666)

抗原

See all GAD (GAD1) 抗体
GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

适用

  • 120
  • 65
  • 58
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马

宿主

  • 93
  • 37
  • 3
  • 2

克隆类型

  • 90
  • 45
多克隆

标记

  • 66
  • 12
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GAD antibody is un-conjugated

应用范围

  • 93
  • 50
  • 25
  • 18
  • 17
  • 15
  • 13
  • 13
  • 13
  • 12
  • 11
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 24
    • 15
    • 11
    • 8
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MASSTPSSSA TSSNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GAD1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GAD1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 594 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

    别名

    GAD1

    背景

    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
    Alias Symbols: FLJ45882, GAD, SCP, CPSQ1
    Protein Interaction Partner: CMTM5, AGTRAP, HAAO, STK3, GAD2, PPP2CA, PRKCE, PPP2CB, PRKACA,
    Protein Size: 594

    分子量

    67 kDa

    基因ID

    2571

    NCBI登录号

    NM_000817, NP_000808

    UniProt

    Q99259
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