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ALAS1 抗体 (N-Term)

This anti-ALAS1 antibody is a 兔 多克隆 antibody detecting ALAS1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊 和 斑马鱼.
产品编号 ABIN2785663
发货至: 中国

Quick Overview for ALAS1 抗体 (N-Term) (ABIN2785663)

抗原

See all ALAS1 抗体
ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼

宿主

  • 55
  • 3

克隆类型

  • 42
  • 16
多克隆

标记

  • 27
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ALAS1 antibody is un-conjugated

应用范围

  • 38
  • 13
  • 12
  • 9
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    ETSAGPSVVS VKTDGGDPSG LLKNFQDIMQ KQRPERVSHL LQDNLPKSVS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against ALAS1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 640 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

    别名

    ALAS1

    背景

    Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
    Alias Symbols: ALAS, ALAS3, ALASH, MIG4
    Protein Interaction Partner: FAM127C, KLHL35, ZNF564, TEKT4, DUSP19, SNX20, MTFR2, LONRF1, ZMAT1, CDC73, TTC23, CERK, SH2D4A, EP400, C2orf42, GNL3L, CCHCR1, POLDIP2, ZFYVE26, USP20, TMSB10, ZNF175, WIPF1, UBC, TMSB4XP6, TMSB4XP2, TMSB4XP1, TMSB4X, TCEA2, PPL, BCL7A, ALAS1, PLAU, VHL,
    Protein Size: 640

    分子量

    70 kDa

    基因ID

    211

    NCBI登录号

    NM_000688, NP_000679

    UniProt

    P13196

    途径

    Regulation of Lipid Metabolism by PPARalpha
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