ALAS1 抗体 (N-Term)
Quick Overview for ALAS1 抗体 (N-Term) (ABIN2785663)
抗原
See all ALAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ETSAGPSVVS VKTDGGDPSG LLKNFQDIMQ KQRPERVSHL LQDNLPKSVS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against ALAS1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 640 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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别名
- ALAS1
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背景
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Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Alias Symbols: ALAS, ALAS3, ALASH, MIG4
Protein Interaction Partner: FAM127C, KLHL35, ZNF564, TEKT4, DUSP19, SNX20, MTFR2, LONRF1, ZMAT1, CDC73, TTC23, CERK, SH2D4A, EP400, C2orf42, GNL3L, CCHCR1, POLDIP2, ZFYVE26, USP20, TMSB10, ZNF175, WIPF1, UBC, TMSB4XP6, TMSB4XP2, TMSB4XP1, TMSB4X, TCEA2, PPL, BCL7A, ALAS1, PLAU, VHL,
Protein Size: 640 -
分子量
- 70 kDa
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基因ID
- 211
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NCBI登录号
- NM_000688, NP_000679
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UniProt
- P13196
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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