Glutathione Reductase 抗体 (N-Term)
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Quick Overview for Glutathione Reductase 抗体 (N-Term) (ABIN2785662)
抗原
See all Glutathione Reductase (GSR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- GSR Antibody - N-terminal region
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序列
- PTIEVSGKKY TAPHILIATG GMPSTPHESQ IPGASLGITS DGFFQLEELP
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against GSR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GSR
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54344-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6093903, (2017) (PubMed).
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- Glutathione Reductase (GSR)
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别名
- GSR
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背景
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Background Information: GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the cytosol. Both glutathione and glutathione reductase are inducible by D3T, and that upregulation of GSH biosynthesis underlies D3T-mediated cytoprotection against ROS/RNS-elicited injury to human vascular smooth muscle cells.
Gene Name: Glutathione reductase
Alternative Symbols: GR, GSRD, HEL-75, HEL-S-122m
Protein Name: Glutathione reductase, mitochondrial
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分子量
- 56kDa
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基因ID
- 2936
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NCBI登录号
- NP_000628
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UniProt
- P00390
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途径
- Thyroid Hormone Synthesis, Cell RedoxHomeostasis
抗原
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