Hexokinase 2 抗体 (Middle Region)
Quick Overview for Hexokinase 2 抗体 (Middle Region) (ABIN2785643)
抗原
See all Hexokinase 2 (HK2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QRIKENKGEE RLRSTIGVDG SVYKKHPHFA KRLHKTVRRL VPGCDVRFLR
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预测反应
- Cow: 79%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HK2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HK2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 917 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Hexokinase 2 (HK2)
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别名
- HK2
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背景
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Alias Symbols: DKFZp686M1669, HKII, HXK2
Protein Interaction Partner: UBQLN1, MAGEA12, SUMO2, SUMO3, UBC, EGFR, rev, H2AFV, WDR61, ARIH2, PDLIM1, PYGL, NUBP1, IPO5, HEXB, FNTA, FBXO6, PARK2, UBD, ITGA4, NUDCD3, UBQLN4, SLC2A4, ELAVL1, PTGDS, ZBTB17, PRKCE, IGFBP4,
Protein Size: 917 -
分子量
- 102 kDa
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基因ID
- 3099
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NCBI登录号
- NM_000189, NP_000180
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UniProt
- P52789
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
抗原
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