APOE 抗体 (N-Term)
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北京 101111
Quick Overview for APOE 抗体 (N-Term) (ABIN2785631)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- APOE Antibody - N-terminal region
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序列
- LMDETMKELK AYKSELEEQL TPVAEETRAR LSKELQAAQA RLGADMEDVC
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预测反应
- Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against APOE. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54284-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- APOE (Apolipoprotein E (APOE))
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别名
- APOE
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背景
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Background Information: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Gene Name: Apolipoprotein E
Alternative Symbols: AD2, LPG, APO-E, ApoE4, LDLCQ5
Protein Name: Apolipoprotein E
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分子量
- 36 kDa
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基因ID
- 348
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NCBI登录号
- NP_000032
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UniProt
- P02649
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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