APOE 抗体 (N-Term)
Quick Overview for APOE 抗体 (N-Term) (ABIN2785631)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LMDETMKELK AYKSELEEQL TPVAEETRAR LSKELQAAQA RLGADMEDVC
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预测反应
- Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against APOE. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Apolipoprotein E (APOE) (AA 19-181) antibody
APOE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 19-168) antibodyAPOE 适用: 大鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 1-172) antibodyAPOE 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 19-168) antibodyAPOE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Apolipoprotein E (APOE) (C-Term) antibodyAPOE 适用: 人 WB, ELISA, IP, ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 200-300) antibodyAPOE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) antibodyAPOE 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Apolipoprotein E (APOE) (N-Term) antibodyAPOE 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 151-250) antibodyAPOE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 14-167) antibodyAPOE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 317 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- APOE (Apolipoprotein E (APOE))
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别名
- APOE
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背景
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Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Alias Symbols: AD2, LDLCQ5, LPG, MGC1571
Protein Interaction Partner: LCAT, ARFGAP1, ALB, C19orf52, LOXL4, PRAM1, MID1IP1, ANKH, FBXL12, FXYD7, ECSIT, PDCD4, IFIT5, MAST1, EPN2, PLEKHA6, CDC37, IQSEC1, LONP1, TYRO3, PRDX2, ST13, RPL4, RHEB, PSEN1, HTRA1, PCMT1, ZNF558, NOS3, IFIT3, GCDH, FOXG1, FARSA, ELAVL1, CYP2C18, CYP2C
Protein Size: 317 -
分子量
- 34 kDa
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基因ID
- 348
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NCBI登录号
- NM_000041, NP_000032
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UniProt
- P02649
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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