IFT122 抗体 (C-Term)
Quick Overview for IFT122 抗体 (C-Term) (ABIN2785593)
抗原
See all IFT122 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QADPAQKDTM LGKFYHFQRL AELYHGYHAI HRHTEDPFSV HRPETLFNIS
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against IFT122. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human IFT122
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1131 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IFT122 (Intraflagellar Transport 122 (IFT122))
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别名
- IFT122
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背景
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IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. IFT122 contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: SPG, WDR10, WDR10p, WDR140, CED
Protein Interaction Partner: UBC, gag-pol,
Protein Size: 1131 -
分子量
- 129 kDa
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基因ID
- 55764
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NCBI登录号
- NM_052990, NP_443716
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UniProt
- Q9HBG6
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途径
- Tube Formation, Embryonic Body Morphogenesis
抗原
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