FBXO31 抗体 (Middle Region)
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北京 101111
Quick Overview for FBXO31 抗体 (Middle Region) (ABIN2785571)
抗原
See all FBXO31 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VAAAEQPAQC GQGQPFVLPV GVSSRNEDYP RTCRMCFYGT GLIAGHGFTS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against FBXO31. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
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anti-F-Box Protein 31 (FBXO31) (AA 1-367) antibody
FBXO31 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) antibodyFBXO31 适用: 人, 犬 WB, FACS 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 151-250) antibodyFBXO31 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 240-539) antibodyFBXO31 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 269-367) antibodyFBXO31 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 431-480) antibodyFBXO31 适用: 人, 小鼠, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 31 (FBXO31) (AA 395-444) antibodyFBXO31 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 367 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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- FBXO31 (F-Box Protein 31 (FBXO31))
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别名
- FBXO31
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背景
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FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CDT1, UBE2L6, UBE2D1, CCND1, CUL1, MAP2K6, PARD6A, SKP1, COPS5, RBX1,
Protein Size: 367 -
分子量
- 40 kDa
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基因ID
- 79791
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NCBI登录号
- NM_024735, NP_079011
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UniProt
- Q5XUX0
抗原
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