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SPAG6 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects SPAG6 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼 和 豚鼠.It has been mentioned in 1 publication
产品编号 ABIN2785513
发货至: 中国
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Quick Overview for SPAG6 抗体 (Middle Region) (ABIN2785513)

抗原

See all SPAG6 抗体
SPAG6 (Sperm Associated Antigen 6 (SPAG6))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼, 豚鼠

宿主

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兔

克隆类型

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多克隆

标记

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This SPAG6 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    原理

    SPAG6 Antibody - middle region

    序列

    HVVGQFSKVL PHDSKARRLF VTSGGLKKVQ EIKAEPGSLL QEYINSINSC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SPAG6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SPAG6
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53681-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • 抗原

    SPAG6 (Sperm Associated Antigen 6 (SPAG6))

    别名

    SPAG6

    背景

    Background Information: SPAG6 is important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

    Gene Name: Sperm associated antigen 6

    Alternative Symbols: pf16, CT141, FAP194, CFAP194, Repro-SA-1

    Protein Name: Sperm-associated antigen 6

    分子量

    56kDa

    基因ID

    9576

    NCBI登录号

    NP_036575

    UniProt

    O75602
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