SPAG6 抗体 (Middle Region)
(1 reference)Quick Overview for SPAG6 抗体 (Middle Region) (ABIN2785513)
抗原
See all SPAG6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- HVVGQFSKVL PHDSKARRLF VTSGGLKKVQ EIKAEPGSLL QEYINSINSC
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SPAG6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SPAG6
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anti-Sperm Associated Antigen 6 (SPAG6) antibody
SPAG6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (AA 1-101) antibodySPAG6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E3 unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (AA 343-428) antibodySPAG6 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) antibodySPAG6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (AA 1-509) antibodySPAG6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (AA 1-458) antibodySPAG6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F3 unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (C-Term) antibodySPAG6 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (AA 431-480) antibodySPAG6 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼, 猴, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 6 (SPAG6) (AA 422-448), (C-Term) antibodySPAG6 适用: 人 WB 宿主: 兔 Polyclonal RB42917 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 509 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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- SPAG6 (Sperm Associated Antigen 6 (SPAG6))
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别名
- SPAG6
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背景
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SPAG6 is important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
Alias Symbols: DKFZp434I153, MGC26276, Repro-SA-1, pf16
Protein Interaction Partner: APP, SPAG16,
Protein Size: 509 -
分子量
- 56 kDa
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基因ID
- 9576
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NCBI登录号
- NM_012443, NP_036575
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UniProt
- O75602
抗原
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