Actl7b 抗体 (Middle Region)
Quick Overview for Actl7b 抗体 (Middle Region) (ABIN2785506)
抗原
See all Actl7b 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KLITIGQERF RCSEMLFQPS LAGSTQPGLP ELTAACLGRC QDTGFKEEMA
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预测反应
- Cow: 77%, Dog: 83%, Human: 100%, Mouse: 85%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against ACTL7B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ACTL7B
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anti-Actin-Like 7b (Actl7b) (AA 1-415) antibody
Actl7b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 7b (Actl7b) (AA 1-415) antibodyActl7b 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 7b (Actl7b) (AA 286-377) antibodyActl7b 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6A4 unconjugated
anti-Actin-Like 7b (Actl7b) (Internal Region) antibodyVerified Actl7b 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Actin-Like 7b (Actl7b) (Internal Region) antibodyVerified Actl7b 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Actin-Like 7b (Actl7b) (AA 1-415) antibodyActl7b 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Actin-Like 7b (Actl7b) (AA 287-336) antibodyActl7b 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 416 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Actl7b (Actin-Like 7b (Actl7b))
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别名
- ACTL7B
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背景
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ACTL7B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
Alias Symbols: Tact1
Protein Interaction Partner: APP,
Protein Size: 416 -
分子量
- 46 kDa
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基因ID
- 10880
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NCBI登录号
- NM_006686, NP_006677
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UniProt
- Q9Y614
抗原
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