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Coilin 抗体 (C-Term)

COIL 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785484
发货至: 中国
  • 抗原 See all Coilin (COIL) 抗体
    Coilin (COIL)
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 43
    • 3
    • 1
    克隆类型
    • 35
    • 12
    多克隆
    标记
    • 23
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Coilin antibody is un-conjugated
    应用范围
    • 32
    • 17
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DYSLLPLLAA APQVGEKIAF KLLELTSSYS PDVSDYKEGR ILSHNPETQQ
    预测反应
    Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 82%
    产品特性
    This is a rabbit polyclonal antibody against COIL. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human COIL
    Top Product
    Discover our top product COIL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 576 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Coilin (COIL)
    别名
    COIL (COIL 产品)
    别名
    p80c antibody, coil antibody, CG8710 antibody, Coilin antibody, Dmel\\CG8710 antibody, LOC100218802 antibody, F3F19.5 antibody, F3F19_5 antibody, CLN80 antibody, p80-coilin antibody, C79982 antibody, Cln80 antibody, p80 antibody, wu:fb08h11 antibody, sph1 antibody, Coilin antibody, coilin antibody, sphere organelles protein-like protein antibody, coilin p80 antibody, coilin L homeolog antibody, p80c antibody, COIL antibody, coil antibody, AT1G13030 antibody, Coil antibody, coil.L antibody
    背景
    COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CLN80, p80-coilin
    Protein Interaction Partner: MFAP1, FGF12, BYSL, WDR34, ZCCHC10, ARMCX1, ZNF277, PDLIM5, CDC23, SNRPF, PTS, POLR2L, PDE4D, DRG1, WWOX, UBL5, CSNK2A2, UBC, VCP, TAF9, LACTB2, KYNU, SMN2, SMN1, GTF2F1, APP, UBD, PLEKHG4, KAZN, PSME3, FAM115A, SART3, PREPL, FXR2, PICK1, FHL5, DNAJA3, KA
    Protein Size: 576
    分子量
    63 kDa
    基因ID
    8161
    NCBI登录号
    NM_004645, NP_004636
    UniProt
    P38432
    途径
    Ribonucleoprotein Complex Subunit Organization
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