Coilin 抗体 (C-Term)
Quick Overview for Coilin 抗体 (C-Term) (ABIN2785484)
抗原
See all Coilin (COIL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DYSLLPLLAA APQVGEKIAF KLLELTSSYS PDVSDYKEGR ILSHNPETQQ
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预测反应
- Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 82%
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产品特性
- This is a rabbit polyclonal antibody against COIL. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human COIL
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anti-Coilin (COIL) (AA 319-538) antibody
COIL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 297-576) antibodyCOIL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 1-576) antibodyCOIL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 477-575) antibodyCOIL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-Coilin (COIL) (AA 1-576) antibodyCOIL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Coilin (COIL) (AA 297-576) antibodyCOIL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 73-86) antibodyVerified COIL 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Coilin (COIL) (AA 460-509) antibodyCOIL 适用: 人, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (C-Term) antibodyCOIL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) antibodyCOIL 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 576 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Coilin (COIL)
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别名
- COIL
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背景
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COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CLN80, p80-coilin
Protein Interaction Partner: MFAP1, FGF12, BYSL, WDR34, ZCCHC10, ARMCX1, ZNF277, PDLIM5, CDC23, SNRPF, PTS, POLR2L, PDE4D, DRG1, WWOX, UBL5, CSNK2A2, UBC, VCP, TAF9, LACTB2, KYNU, SMN2, SMN1, GTF2F1, APP, UBD, PLEKHG4, KAZN, PSME3, FAM115A, SART3, PREPL, FXR2, PICK1, FHL5, DNAJA3, KA
Protein Size: 576 -
分子量
- 63 kDa
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基因ID
- 8161
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NCBI登录号
- NM_004645, NP_004636
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UniProt
- P38432
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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