Importin 5 抗体 (N-Term)
Quick Overview for Importin 5 抗体 (N-Term) (ABIN2785469)
抗原
See all Importin 5 (IPO5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GNNQWPEGLK FLFDSVSSQN VGLREAALHI FWNFPGIFGN QQQHYLDVIK
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against RANBP5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RANBP5
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anti-Importin 5 (IPO5) (AA 1-100) antibody
IPO5 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Importin 5 (IPO5) (AA 20-300) antibodyIPO5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) (AA 1-1115) antibodyIPO5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Importin 5 (IPO5) antibodyIPO5 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) antibodyIPO5 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) (AA 1-101) antibodyIPO5 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Importin 5 (IPO5) antibodyIPO5 适用: 人, 大鼠, 小鼠 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Importin 5 (IPO5) (AA 143-192) antibodyIPO5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1115 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Importin 5 (IPO5)
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别名
- RANBP5
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背景
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Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Alias Symbols: DKFZp686O1576, FLJ43041, IMB3, KPNB3, MGC2068, RANBP5, imp5
Protein Interaction Partner: HUWE1, UBC, STAU1, ASB15, HK2, HEXB, ATIC, MCTS1, TNFAIP8, EZR, UBA1, TXNRD1, FBXO6, BHLHB9, EGFR, MUC1, SOX2, NPM1, HDAC2, LAS1L, PELP1, WASL, VCAM1, MAP1LC3A, ITGA4, FN1, CFTR, RPL7, CA9, NOTCH1, IPO4, TNPO1, KPNB1, RAN, CUL3, ACD, TINF2, TERF1, BKRF1,
Protein Size: 1115 -
分子量
- 125 kDa
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基因ID
- 3843
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NCBI登录号
- NM_002271, NP_002262
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途径
- Protein targeting to Nucleus
抗原
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