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Inhibin alpha 抗体 (N-Term)

INHA 适用: 人, 小鼠, 大鼠, Pig, Cow, 绵羊, 兔, 犬, 山羊, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785468
发货至: 中国
  • 抗原 See all Inhibin alpha (INHA) 抗体
    Inhibin alpha (INHA) (Inhibin, alpha (INHA))
    抗原表位
    • 15
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Pig, Cow, 绵羊, 兔, 犬, 山羊, 马, Saccharomyces cerevisiae
    宿主
    • 108
    • 22
    • 2
    克隆类型
    • 109
    • 24
    多克隆
    标记
    • 62
    • 21
    • 18
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Inhibin alpha antibody is un-conjugated
    应用范围
    • 106
    • 62
    • 48
    • 26
    • 26
    • 23
    • 17
    • 12
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP
    预测反应
    Cow: 100%, Dog: 86%, Goat: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 93%, Sheep: 100%, Yeast: 79%
    产品特性
    This is a rabbit polyclonal antibody against INHA. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human INHA
    Top Product
    Discover our top product INHA Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 366 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Inhibin alpha (INHA) (Inhibin, alpha (INHA))
    别名
    INHA (INHA 产品)
    别名
    si:dkey-91f15.2 antibody, INHA antibody, MGC108500 antibody, AW555078 antibody, inhibin, alpha antibody, inhibin alpha subunit antibody, inhibin alpha antibody, inhibin alpha L homeolog antibody, inha antibody, INHA antibody, inha.L antibody, Inha antibody
    背景
    INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: SIAH1, TGFBR3, INHBB, INHBA, FST, ACVR2A,
    Protein Size: 366
    分子量
    40 kDa
    基因ID
    3623
    NCBI登录号
    NM_002191, NP_002182
    UniProt
    P05111
    途径
    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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