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Inhibin alpha 抗体 (N-Term)

The 兔 多克隆 anti-Inhibin alpha antibody (ABIN2785468) specifically detects Inhibin alpha in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, Pig, 绵羊, 兔, 犬, 山羊, 马 和 Saccharomyces cerevisiae samples.
产品编号 ABIN2785468
发货至: 中国
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Quick Overview for Inhibin alpha 抗体 (N-Term) (ABIN2785468)

抗原

See all Inhibin alpha (INHA) 抗体
Inhibin alpha (INHA) (Inhibin, alpha (INHA))

适用

人, 小鼠, 大鼠, Cow, Pig, 绵羊, 兔, 犬, 山羊, 马, Saccharomyces cerevisiae

宿主

  • 158
  • 46
  • 2
兔

克隆类型

  • 129
  • 78
多克隆

标记

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This Inhibin alpha antibody is un-conjugated

应用范围

  • 137
  • 73
  • 49
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  • 27
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  • 21
  • 12
  • 8
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  • 3
  • 1
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  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 22
    • 15
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    N-Term

    原理

    INHA Antibody - N-terminal region

    序列

    GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP

    预测反应

    Cow: 100%, Dog: 86%, Goat: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 93%, Sheep: 100%, Yeast: 79%

    产品特性

    This is a rabbit polyclonal antibody against INHA. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human INHA
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53597-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Inhibin alpha (INHA) (Inhibin, alpha (INHA))

    别名

    INHA

    背景

    Background Information: INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Inhibin, alpha

    Alternative Symbols: -

    Protein Name: Inhibin alpha chain

    分子量

    40 kDa

    基因ID

    3623

    NCBI登录号

    NP_002182

    UniProt

    P05111

    途径

    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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