Inhibin alpha 抗体 (N-Term)
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Quick Overview for Inhibin alpha 抗体 (N-Term) (ABIN2785468)
抗原
See all Inhibin alpha (INHA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP
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预测反应
- Cow: 100%, Dog: 86%, Goat: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 93%, Sheep: 100%, Yeast: 79%
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产品特性
- This is a rabbit polyclonal antibody against INHA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human INHA
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anti-Inhibin, alpha (INHA) (AA 301-366) antibody
INHA 适用: 大鼠, 小鼠, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 25-363) antibodyINHA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 19-366) antibodyINHA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 233-362) antibodyINHA 适用: 人 IHC 宿主: 兔 Monoclonal 561R unconjugated Recombinant Antibody
anti-Inhibin, alpha (INHA) antibodyINHA 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Inhibin, alpha (INHA) (AA 79-108), (N-Term) antibodyINHA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18802 unconjugated
anti-Inhibin, alpha (INHA) (AA 281-366) antibodyINHA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 233-366) antibodyINHA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 240-366) antibodyINHA 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 25-363) antibodyINHA 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 366 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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别名
- INHA
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背景
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INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: SIAH1, TGFBR3, INHBB, INHBA, FST, ACVR2A,
Protein Size: 366 -
分子量
- 40 kDa
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基因ID
- 3623
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NCBI登录号
- NM_002191, NP_002182
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UniProt
- P05111
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途径
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
抗原
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