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Aurora Kinase C 抗体 (Middle Region)

Cited in 1 publication. The 兔 多克隆 anti-Aurora Kinase C antibody (ABIN2785453) specifically detects Aurora Kinase C in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2785453
发货至: 中国
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Quick Overview for Aurora Kinase C 抗体 (Middle Region) (ABIN2785453)

抗原

See all Aurora Kinase C (AURKC) 抗体
Aurora Kinase C (AURKC)

适用

人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 64
  • 4
  • 1

克隆类型

  • 67
  • 2
多克隆

标记

  • 35
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aurora Kinase C antibody is un-conjugated

应用范围

  • 56
  • 30
  • 20
  • 14
  • 12
  • 4
  • 3
  • 1
Western Blotting (WB)
  • 抗原表位

    • 9
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    TYDEKVDLWC IGVLCYELLV GYPPFESASH SETYRRILKV DVRFPLSMPL

    预测反应

    Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against AURKC. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human AURKC
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 309 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Lim, Park, Lee, Han, Kim, Cheang, Lee, Lee, Ko, Jang, Kim, Miniaci, Bartsch, Kim, Bailey, Kandel, Kaang: "Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." in: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).

  • 抗原

    Aurora Kinase C (AURKC)

    别名

    AURKC

    背景

    AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
    Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5
    Protein Interaction Partner: SRPK1, AURKB, HIST1H3A, INCENP, BIRC5, TACC2, UBC, HSP90AA1, BRCA1, LNX1, NEDD4L, NEDD4, CENPA,
    Protein Size: 309

    分子量

    34 kDa

    基因ID

    6795

    NCBI登录号

    NM_001015878, NP_001015878

    UniProt

    Q9UQB9

    途径

    Cell Division Cycle, Maintenance of Protein Location
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