Aurora Kinase C 抗体 (Middle Region)
Quick Overview for Aurora Kinase C 抗体 (Middle Region) (ABIN2785453)
抗原
See all Aurora Kinase C (AURKC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- TYDEKVDLWC IGVLCYELLV GYPPFESASH SETYRRILKV DVRFPLSMPL
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预测反应
- Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against AURKC. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human AURKC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 309 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." in: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).
: "
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Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." in: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).
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- Aurora Kinase C (AURKC)
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别名
- AURKC
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背景
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AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5
Protein Interaction Partner: SRPK1, AURKB, HIST1H3A, INCENP, BIRC5, TACC2, UBC, HSP90AA1, BRCA1, LNX1, NEDD4L, NEDD4, CENPA,
Protein Size: 309 -
分子量
- 34 kDa
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基因ID
- 6795
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NCBI登录号
- NM_001015878, NP_001015878
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UniProt
- Q9UQB9
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途径
- Cell Division Cycle, Maintenance of Protein Location
抗原
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