Aurora A 抗体 (Middle Region)
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北京 101111
Quick Overview for Aurora A 抗体 (Middle Region) (ABIN2785452)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human AURKA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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别名
- AURKA
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背景
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AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7
Protein Interaction Partner: CHFR, GADD45A, RPLP2, RPLP0, RPL38, RPL30, RPL27, RPL22, RPL12, RPL11, PSMB7, PSMB5, PSMA6, PSMA5, PSMA1, MAPK6, PPP6C, PCMT1, YBX1, NPM1, NCL, MFAP4, LYZ, ILF3, ILF2, IARS, HSPD1, HSP90AB1, HSP90AA1, HSPA9, HSPA8, HSPA5, HSPA2, HSPA1A, HNRNPU, HNRNPA2B1,
Protein Size: 403 -
分子量
- 44 kDa
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基因ID
- 6790
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NCBI登录号
- NM_198437, NP_940839
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UniProt
- O14965
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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