GRK4 抗体 (Middle Region)
Quick Overview for GRK4 抗体 (Middle Region) (ABIN2785447)
抗原
See all GRK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QSRFVVSLAY AYETKDALCL VLTIMNGGDL KFHIYNLGNP GFDEQRAVFY
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预测反应
- Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against GRK4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GRK4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 532 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))
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别名
- GRK4
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背景
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GRK4 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. GRK4 has been linked to both genetic and acquired hypertension.This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension.
Alias Symbols: GPRK2L, GPRK4, GRK4a, IT11
Protein Interaction Partner: HSP90AA1, UBC, NEDD4, IKBKG, FSHR, CALM1, BDKRB2,
Protein Size: 532 -
分子量
- 59 kDa
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基因ID
- 2868
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NCBI登录号
- NM_001004057, NP_001004057
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UniProt
- P32298
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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