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GSTM3 抗体 (Middle Region)

The 兔 多克隆 anti-GSTM3 antibody is suitable to detect GSTM3 in samples from 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔 和 马. It has been validated for WB.
产品编号 ABIN2785444
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GSTM3 抗体 (Middle Region) (ABIN2785444)

抗原

See all GSTM3 抗体
GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

适用

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人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 马

宿主

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兔

克隆类型

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多克隆

标记

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This GSTM3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    原理

    GSTM3 Antibody - middle region

    序列

    EEKIRVDIIE NQVMDFRTQL IRLCYSSDHE KLKPQYLEEL PGQLKQFSMF

    预测反应

    Cow: 85%, Dog: 77%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 86%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against GSTM3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human GSTM3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101685

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

    别名

    GSTM3

    背景

    Background Information: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM3 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Glutathione S-transferase mu 3 (brain)

    Alternative Symbols: GST5, GSTB, GTM3, GSTM3-3

    Protein Name: Glutathione S-transferase Mu 3

    分子量

    27 kDa

    基因ID

    2947

    NCBI登录号

    NP_000840

    UniProt

    P21266
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