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LRRC50 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects LRRC50 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 斑马鱼. It has been mentioned in 3+ publications
产品编号 ABIN2785360
发货至: 中国
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Quick Overview for LRRC50 抗体 (N-Term) (ABIN2785360)

抗原

See all LRRC50 抗体
LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

适用

  • 9
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼

宿主

  • 5
  • 4

克隆类型

  • 5
  • 4
多克隆

标记

  • 9
This LRRC50 antibody is un-conjugated

应用范围

  • 8
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 2
    • 1
    • 1
    N-Term

    序列

    LNDTLYLHFK GFDRIENLEE YTGLRCLWLQ SNGIQKIENL EAQTELRCLF

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against LRRC50. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC50
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 725 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Basten, Davis, Gillis, van Rooijen, Stoop, Babala, Logister, Heath, Jonges, Katsanis, Voest, van Eeden, Medema, Ketting, Schulte-Merker, Looijenga, Giles: "Mutations in LRRC50 predispose zebrafish and humans to seminomas." in: PLoS genetics, Vol. 9, Issue 4, pp. e1003384, (2013) (PubMed).

    Yang, Zhou, Ma, Wang, Chen, Meng, Yu, Zhou, Sun: "Knockdown of PPAR δ gene promotes the growth of colon cancer and reduces the sensitivity to bevacizumab in nude mice model." in: PLoS ONE, Vol. 8, Issue 4, pp. e60715, (2013) (PubMed).

    Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原

    LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

    别名

    LRRC50

    背景

    LRRC50 contains 6 LRR (leucine-rich) repeats. It is proposed that LRRC50 to be a novel candidate gene for human cystic kidney disease, involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
    Alias Symbols: DKFZp434A119, FLJ25330, ODA7, CILD13, LRRC50
    Protein Interaction Partner: UBC,
    Protein Size: 725

    分子量

    80 kDa

    基因ID

    123872

    NCBI登录号

    NM_178452, NP_848547

    UniProt

    Q8NEP3
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