H1FOO 抗体 (N-Term)
(2 references)Quick Overview for H1FOO 抗体 (N-Term) (ABIN2785287)
抗原
See all H1FOO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MAPGSVTSDI SPSSTSTAGS SRSPESEKPG PSHGGVPPGG PSHSSLPVGR
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预测反应
- Human: 100%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against H1FOO. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human H1FOO
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anti-H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (Internal Region) antibody
H1FOO 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (AA 1-207) antibodyH1FOO 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (C-Term) antibodyH1FOO 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (N-Term) antibodyH1FOO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 346 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Repetitive interactions observed in the crystal structure of a collagen-model peptide, [(Pro-Pro-Gly)9]3." in: Journal of biochemistry, Vol. 138, Issue 2, pp. 135-44, (2005) (PubMed).
: "H1FOO is coupled to the initiation of oocytic growth." in: Biology of reproduction, Vol. 72, Issue 1, pp. 135-42, (2004) (PubMed).
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: "Repetitive interactions observed in the crystal structure of a collagen-model peptide, [(Pro-Pro-Gly)9]3." in: Journal of biochemistry, Vol. 138, Issue 2, pp. 135-44, (2005) (PubMed).
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- H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
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别名
- H1FOO
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背景
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H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.
Alias Symbols: MGC50807, osH1
Protein Size: 346 -
分子量
- 36 kDa
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基因ID
- 132243
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NCBI登录号
- NM_153833, NP_722575
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UniProt
- Q8IZA3
抗原
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