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TMPRSS6 抗体 (N-Term)

TMPRSS6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785278
发货至: 中国
  • 抗原 See all TMPRSS6 抗体
    TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    N-Term
    适用
    • 45
    • 7
    • 7
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig
    宿主
    • 43
    • 2
    克隆类型
    • 45
    多克隆
    标记
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMPRSS6 antibody is un-conjugated
    应用范围
    • 39
    • 21
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LLWYFLGYKA EVMVSQVYSG SLRVLNRHFS QDLTRRESSA FRSETAKAQK
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against TMPRSS6. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS6
    Top Product
    Discover our top product TMPRSS6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 811 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
    别名
    TMPRSS6 (TMPRSS6 产品)
    别名
    IRIDA antibody, 1300008A22Rik antibody, transmembrane protease, serine 6 antibody, transmembrane serine protease 6 antibody, Tmprss6 antibody, TMPRSS6 antibody
    背景
    TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
    Alias Symbols: IRIDA
    Protein Interaction Partner: LAMA1, FN1, COL1A1,
    Protein Size: 811
    分子量
    90 kDa
    基因ID
    164656
    NCBI登录号
    NM_153609, NP_705837
    UniProt
    Q8IU80
    途径
    Transition Metal Ion Homeostasis
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