TMPRSS6 抗体 (N-Term)
Quick Overview for TMPRSS6 抗体 (N-Term) (ABIN2785278)
抗原
See all TMPRSS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LLWYFLGYKA EVMVSQVYSG SLRVLNRHFS QDLTRRESSA FRSETAKAQK
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TMPRSS6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS6
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anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 98-301) antibody
TMPRSS6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 85-114), (N-Term) antibodyTMPRSS6 适用: 人 WB 宿主: 兔 Polyclonal RB39227 unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 71-120) antibodyTMPRSS6 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 711-811) antibodyTMPRSS6 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 1-461) antibodyTMPRSS6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 811 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
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别名
- TMPRSS6
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背景
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TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
Alias Symbols: IRIDA
Protein Interaction Partner: LAMA1, FN1, COL1A1,
Protein Size: 811 -
分子量
- 90 kDa
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基因ID
- 164656
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NCBI登录号
- NM_153609, NP_705837
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UniProt
- Q8IU80
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途径
- Transition Metal Ion Homeostasis
抗原
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