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Sphingomyelin Synthase 2 抗体 (N-Term)

SGMS2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785219
发货至: 中国
  • 抗原 See all Sphingomyelin Synthase 2 (SGMS2) 抗体
    Sphingomyelin Synthase 2 (SGMS2)
    抗原表位
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 25
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼
    宿主
    • 23
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    This Sphingomyelin Synthase 2 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    KFPLEWWKTG IAFIYAVFNL VLTTVMITVV HERVPPKELS PPLPDKFFDY
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against SGMS2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SGMS2
    Top Product
    Discover our top product SGMS2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 365 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Sphingomyelin Synthase 2 (SGMS2)
    别名
    SGMS2 (SGMS2 产品)
    别名
    SMS2 antibody, 4933405A16Rik antibody, 5133401H06Rik antibody, AI854299 antibody, RGD1305778 antibody, spermatin antibody, sphingomyelin synthase 2 antibody, sgms2 antibody, SGMS2 antibody, Sgms2 antibody
    背景
    SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).[supplied by OMIM]. Sequence Note: removed 3 bases from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2142 BC041369.2 4-2145
    Alias Symbols: MGC26963, SMS2
    Protein Interaction Partner: UBC,
    Protein Size: 365
    分子量
    42 kDa
    基因ID
    166929
    NCBI登录号
    NM_152621, NP_689834
    UniProt
    Q8NHU3
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