Sphingomyelin Synthase 2 抗体 (N-Term)
Quick Overview for Sphingomyelin Synthase 2 抗体 (N-Term) (ABIN2785218)
抗原
See all Sphingomyelin Synthase 2 (SGMS2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KFPLEWWKTG IAFIYAVFNL VLTTVMITVV HERVPPKELS PPLPDKFFDY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against SGMS2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SGMS2
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anti-Sphingomyelin Synthase 2 (SGMS2) (AA 2-80) antibody
SGMS2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 7D10 unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 1-79) antibodySGMS2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 338-365), (C-Term) antibodySGMS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB24438 unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) antibodySGMS2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) antibodySGMS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 336-365), (C-Term) antibodySGMS2 适用: 人 WB, FACS, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 71-120) antibodySGMS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (N-Term) antibodySGMS2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 365 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Sphingomyelin Synthase 2 (SGMS2)
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别名
- SGMS2
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背景
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SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).[supplied by OMIM]. Sequence Note: removed 3 bases from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2142 BC041369.2 4-2145
Alias Symbols: MGC26963, SMS2
Protein Interaction Partner: UBC,
Protein Size: 365 -
分子量
- 42 kDa
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基因ID
- 166929
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NCBI登录号
- NM_152621, NP_689834
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UniProt
- Q8NHU3
抗原
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