Nesprin3 抗体 (N-Term)
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北京 101111
Quick Overview for Nesprin3 抗体 (N-Term) (ABIN2785211)
抗原
See all Nesprin3 (C14orf49) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AQVLLHNVDN QAVLLDRLLE EAASLFNRIG DPSVDEDAQK RMKAEYDAVK
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预测反应
- Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SYNE3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SYNE3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
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别名
- SYNE3
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背景
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SYNE3 is a component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. It is involved in the maintenance of nuclear organization and structural integrity. It is a probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. SYNE3 plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Protein Size: 596 -
分子量
- 65 kDa
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基因ID
- 161176
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途径
- Maintenance of Protein Location
抗原
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