FBXO32 抗体 (N-Term)
Quick Overview for FBXO32 抗体 (N-Term) (ABIN2785130)
抗原
See all FBXO32 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QQQLNNIQIT RPAFKGLTFT DLPLCLQLNI MQRLSDGRDL VSLGQAAPDL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against FBXO32. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO32
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 210 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXO32 (F-Box Protein 32 (FBXO32))
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别名
- FBXO32
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背景
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
Alias Symbols: FLJ32424, Fbx32, MAFbx, MGC33610
Protein Interaction Partner: UBC, MLH1, Mutyh, UBE2D3, KHDRBS3, SERPINB5, CDC34, DUSP1, FBXO25, MYBPC3, CDKN1A, EIF3F, SKP1, EIF3A,
Protein Size: 210 -
分子量
- 25 kDa
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基因ID
- 114907
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NCBI登录号
- NM_148177, NP_680482
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UniProt
- Q0VAQ6
抗原
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