TRAF3IP2 抗体 (N-Term)
Quick Overview for TRAF3IP2 抗体 (N-Term) (ABIN2785129)
抗原
See all TRAF3IP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- IPVEVDESEP YPSQLLKPIP EYSPEEESEP PAPNIRNMAP NSLSAPTMLH
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预测反应
- Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against TRAF3IP2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRAF3IP2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 574 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))
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别名
- TRAF3IP2
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背景
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This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Alias Symbols: ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581, PSORS13
Protein Interaction Partner: RIMBP3, IL17RA, MRPL28, STK16, UBE2V1, TRIP6, TRAF6, SYK, SRSF1, FHL3, ELAVL1, TRAF2, FBXW11, BTRC, UBC, Dlg4, TBK1, IKBKE, TNFRSF13C, TRAF3, CD40, MAP3K7, TRAF3IP2, IKBKG, IKBKB, CHUK, IL17A, MDFI, TRAF5, TRAF1,
Protein Size: 574 -
分子量
- 65 kDa
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基因ID
- 10758
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NCBI登录号
- NM_147200, NP_671733
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UniProt
- O43734
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途径
- Production of Molecular Mediator of Immune Response
抗原
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