FBXW10 抗体 (Middle Region)
Quick Overview for FBXW10 抗体 (Middle Region) (ABIN2784922)
抗原
See all FBXW10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RKIHLLDIIQ VKAIPVEFRG HAGSVRALFL CEEENFLLSG SYDLSIRYWD
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against FBXW10. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FBXW10
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anti-F-Box and WD Repeat Domain Containing 10 (FBXW10) (AA 432-481) antibody
FBXW10 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 10 (FBXW10) (Middle Region) antibodyFBXW10 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 10 (FBXW10) (N-Term) antibodyFBXW10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1051 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))
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别名
- FBXW10
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背景
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Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbw10, HREP, SM25H2, SM2SH2
Protein Interaction Partner: CUL5,
Protein Size: 1051 -
分子量
- 120 kDa
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基因ID
- 10517
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NCBI登录号
- NM_031456, NP_113644
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UniProt
- Q5XX13
抗原
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