CAPN10 抗体 (N-Term)
Quick Overview for CAPN10 抗体 (N-Term) (ABIN2784913)
抗原
See all CAPN10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MRAGRGATPA RELFRDAAFP AADSSLFCDL STPLAQFRED ITWRRPQEIC
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against CAPN10. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAPN10
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anti-Calpain 10 (CAPN10) (AA 1-672) antibody
CAPN10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (N-Term) antibodyCAPN10 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (N-Term) antibodyCAPN10 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (AA 44-93) antibodyCAPN10 适用: 人, 小鼠, 犬, 兔, 豚鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (N-Term) antibodyCAPN10 适用: 人, 犬, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (AA 1-230) antibodyCAPN10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (AA 22-374) antibodyCAPN10 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 517 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CAPN10 (Calpain 10 (CAPN10))
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别名
- CAPN10
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背景
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CAPN10 is the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CANP10, NIDDM1
Protein Interaction Partner: EFNB1, FLOT1, PSMA7, FANCC,
Protein Size: 517 -
分子量
- 58 kDa
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基因ID
- 11132
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NCBI登录号
- NM_023085, NP_075573
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UniProt
- Q9HC96
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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