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CRY2 抗体 (N-Term)

This anti-CRY2 antibody is a 兔 多克隆 antibody detecting CRY2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2784909
发货至: 中国

Quick Overview for CRY2 抗体 (N-Term) (ABIN2784909)

抗原

See all CRY2 抗体
CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This CRY2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    N-Term

    序列

    IELNGQKPPL TYKRFQAIIS RMELPKKPVG LVTSQQMESC RAEIQENHDE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against CRY2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CRY2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 593 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Currie, Doherty, Sillar: "Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. 6053-8, (2016) (PubMed).

  • 抗原

    CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

    别名

    CRY2

    背景

    CRY2 is a blue light-dependent regulator of the circadian feedback loop.CRY2 inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. CRY2 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity.CRY2 has no photolyase activity. CRY2 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus.CRY2 may inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
    Alias Symbols: FLJ10332, HCRY2, KIAA0658, PHLL2
    Protein Interaction Partner: MTUS2, PDE9A, CTBP1, UBC, FBXL3, FBXL21, BTRC, CUL1, SKP1, ATXN1, Csnk1e, PER3, PER2, PER1, PPP5C, TTC1, CRY2, TIMELESS,
    Protein Size: 593

    分子量

    67 kDa

    基因ID

    1408

    NCBI登录号

    NM_021117, NP_066940

    UniProt

    Q49AN0

    途径

    Response to Water Deprivation, Protein targeting to Nucleus
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