Dynamin 1-Like 抗体 (N-Term)
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北京 101111
Quick Overview for Dynamin 1-Like 抗体 (N-Term) (ABIN2784887)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- DNM1L Antibody - N-terminal region
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序列
- IRQEIENETE RISGNNKGVS PEPIHLKIFS PNVVNLTLVD LPGMTKVPVG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against DNM1L. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52329-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 10, pp. 1457-70, (2014) (PubMed).
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- Dynamin 1-Like (DNM1L)
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别名
- DNM1L
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背景
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Background Information: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Gene Name: Dynamin 1-like
Alternative Symbols: DLP1, DRP1, DVLP, EMPF, OPA5, EMPF1, DYMPLE, HDYNIV
Protein Name: Dynamin-1-like protein
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分子量
- 82 kDa
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基因ID
- 10059
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NCBI登录号
- NP_036192
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UniProt
- O00429
抗原
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