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Dynamin 1-Like 抗体 (N-Term)

Cited in 1 publication. This anti-Dynamin 1-Like antibody is a 兔 多克隆 antibody detecting Dynamin 1-Like in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae 和 斑马鱼.
产品编号 ABIN2784887
发货至: 中国
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Quick Overview for Dynamin 1-Like 抗体 (N-Term) (ABIN2784887)

抗原

See all Dynamin 1-Like (DNM1L) 抗体
Dynamin 1-Like (DNM1L)

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This Dynamin 1-Like antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    IRQEIENETE RISGNNKGVS PEPIHLKIFS PNVVNLTLVD LPGMTKVPVG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against DNM1L. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 736 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Su, Chiu, Hung, Hong: "Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 10, pp. 1457-70, (2014) (PubMed).

  • 抗原

    Dynamin 1-Like (DNM1L)

    别名

    DNM1L

    背景

    The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
    Alias Symbols: DLP1, DRP1, DVLP, DYMPLE, HDYNIV, VPS1, EMPF, DYNIV-11
    Protein Interaction Partner: ZBTB24, UBC, SCG3, SH3GL1, RRM2, MAGEA3, MAGEA1, MARCH5, EGFR, VPS26A, SSB, CARS, ATP6V1C1, APEH, PSMG3, FAM129B, TBC1D15, CYHR1, ARFIP1, JMJD6, SEC24A, SOX2, DNM1L, MIEF2, MFF, PEX14, LRRK2, MIEF1, COPS5, GABRR1, MUL1, SUMO2, PARK2, PEX25, PEX11G, PEX11A
    Protein Size: 736

    分子量

    82 kDa

    基因ID

    10059

    NCBI登录号

    NM_012062, NP_036192

    UniProt

    O00429
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