KATNA1 抗体 (C-Term)
Quick Overview for KATNA1 抗体 (C-Term) (ABIN2784857)
抗原
See all KATNA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against Katna1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 491 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
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别名
- Katna1
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背景
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Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.
Alias Symbols: -
Protein Interaction Partner: KATNB1,
Protein Size: 491 -
分子量
- 54 kDa
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基因ID
- 23924
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NCBI登录号
- NM_011835, NP_035965
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UniProt
- Q9WV86
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途径
- Microtubule Dynamics
抗原
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