GRAP 抗体 (Middle Region)
Quick Overview for GRAP 抗体 (Middle Region) (ABIN2784825)
抗原
See all GRAP 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- Middle Region
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                                            序列
- KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD
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                                            预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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                                            产品特性
- This is a rabbit polyclonal antibody against GRAP. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GRAP
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
- 
                        Antigen size: 217 AA 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - GRAP (GRB2-Related Adaptor Protein (GRAP))
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                                            别名
- GRAP
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                                            背景
- 
                        This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. 
 Alias Symbols: MGC64880
 Protein Interaction Partner: TRIM21, RBPMS, UBC, ARHGAP32, KHDRBS1, LAT, SHC1, SOS1, PLCG1, KIT, LCK, FYN, FASLG, EPOR, GAB2,
 Protein Size: 217
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                                            分子量
- 25 kDa
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                                            基因ID
- 10750
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                                            NCBI登录号
- NM_006613, NP_006604
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                                            UniProt
- Q13588
 抗原
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