HAX1 抗体 (Middle Region)
Quick Overview for HAX1 抗体 (Middle Region) (ABIN2784795)
抗原
See all HAX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LPGPESETPG ERLREGQTLR DSMLKYPDSH QPRIFGGVLE SDARSESPQP
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against HAX1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HAX1
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anti-HCLS1 Associated Protein X-1 (HAX1) antibody
HAX1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 2-250) antibodyHAX1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 76-174) antibodyHAX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 1-279) antibodyHAX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 1-279) antibodyHAX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (C-Term) antibodyHAX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) antibodyHAX1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 191-279) antibodyHAX1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (Internal Region) antibodyVerified HAX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 107-156) antibodyHAX1 适用: 人, 小鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 279 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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别名
- HAX1
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背景
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HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HCLSBP1, HS1BP1, SCN3
Protein Interaction Partner: ERLIN2, UBC, BIRC3, CEP250, TUBGCP2, TUBGCP3, MAPK10, HIPK1, DYRK4, ZNF420, POLR1D, ZNRD1, RBX1, STAT5B, RPA1, PPP3CC, CFTR, EWSR1, SHC1, HTRA2, NEDD4L, CUL3, CUL4A, PIDD1, SVIL, EBNA-LP, AMFR, HNF4G, AKAP10, TUBB4A, ABCC4, MATN4, EIF3D, RGS1, HSP90AB1, H
Protein Size: 279 -
分子量
- 31 kDa
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基因ID
- 10456
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NCBI登录号
- NM_006118, NP_006109
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UniProt
- O00165
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途径
- Regulation of Actin Filament Polymerization
抗原
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