DLC1 抗体 (C-Term)
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北京 101111
Quick Overview for DLC1 抗体 (C-Term) (ABIN2784792)
抗原
See all DLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- DLC1 Antibody - C-terminal region
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序列
- NLAVCLAPSL FHLNTLKREN SSPRVMQRKQ SLGKPDQKDL NENLAATQGL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against DLC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1
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anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibody
Verified DLC1 适用: 人, 小鼠 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 204-463) antibodyDLC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibodyDLC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibodyDLC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1224-1273) antibodyDLC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (C-Term) antibodyDLC1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1-1528) antibodyDLC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1-1528) antibodyDLC1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098745
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DLC1 (Deleted in Liver Cancer 1 (DLC1))
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别名
- DLC1
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背景
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Background Information: This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
Gene Name: Deleted in liver cancer 1
Alternative Symbols: HP, ARHGAP7, STARD12, p122-RhoGAP
Protein Name: Deleted in lung and esophageal cancer protein 1
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分子量
- 52kDa
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基因ID
- 10395
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UniProt
- Q9Y238
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途径
- Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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