DLC1 抗体 (C-Term)
-
- 抗原 See all DLC1 抗体
- DLC1 (Deleted in Liver Cancer 1 (DLC1))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DLC1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- NLAVCLAPSL FHLNTLKREN SSPRVMQRKQ SLGKPDQKDL NENLAATQGL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against DLC1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1
- Top Product
- Discover our top product DLC1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 467 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- DLC1 (Deleted in Liver Cancer 1 (DLC1))
- 别名
- DLC1 (DLC1 产品)
- 别名
- ARHGAP7 antibody, HP antibody, STARD12 antibody, p122-RhoGAP antibody, rhogap7 antibody, DLC-1 antibody, StARD12 antibody, Dlc-1 antibody, A730069N07Rik antibody, Arhgap7 antibody, dlc-1 antibody, RhoGAP antibody, Dlc1 antibody, DLC1 Rho GTPase activating protein antibody, DLC1 Rho GTPase activating protein S homeolog antibody, rho GTPase-activating protein 7 antibody, deleted in liver cancer 1 antibody, DLC1 antibody, dlc1.S antibody, dlc1 antibody, LOC100456847 antibody, Dlc1 antibody, LOC100729904 antibody
- 背景
-
This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
Alias Symbols: ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
Protein Interaction Partner: DDB1, FBXW5, CUL1, CUL2, CUL3, CUL4A, UBC, TENC1, CAV1, S100A10, WWC1, AKT1,
Protein Size: 467 - 分子量
- 52 kDa
- 基因ID
- 10395
- NCBI登录号
- NM_001164271
- UniProt
- Q9Y238
- 途径
- Tube Formation, Positive Regulation of Endopeptidase Activity
-