DLC1 抗体 (C-Term)
Quick Overview for DLC1 抗体 (C-Term) (ABIN2784792)
抗原
See all DLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NLAVCLAPSL FHLNTLKREN SSPRVMQRKQ SLGKPDQKDL NENLAATQGL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against DLC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 467 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DLC1 (Deleted in Liver Cancer 1 (DLC1))
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别名
- DLC1
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背景
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This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
Alias Symbols: ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
Protein Interaction Partner: DDB1, FBXW5, CUL1, CUL2, CUL3, CUL4A, UBC, TENC1, CAV1, S100A10, WWC1, AKT1,
Protein Size: 467 -
分子量
- 52 kDa
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基因ID
- 10395
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NCBI登录号
- NM_001164271
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UniProt
- Q9Y238
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途径
- Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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