Protein Tob1 (TOB1) (Middle Region) 抗体
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北京 101111
Quick Overview for Protein Tob1 (TOB1) (Middle Region) 抗体 (ABIN2784777)
抗原
See all Protein Tob1 (TOB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT
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预测反应
- Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 92%, Yeast: 100%
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产品特性
- This is a rabbit polyclonal antibody against TOB1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TOB1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 345 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Protein Tob1 (TOB1)
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别名
- TOB1
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背景
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This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alias Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
Protein Interaction Partner: CORO7, APP, DTL, CDC7, PABPC1, CHAF1A, PAN2, UBR5, ELAVL1, SMAD3, CTNNB1, UBC, SKP2, SCMH1, MARCKS, SETDB1, CNOT7, SMAD9, SMAD5, SMAD6, SMAD1, SMAD2, SMAD4, MAPK1, ERBB2, RPS6KA1, MAPK9,
Protein Size: 345 -
分子量
- 38 kDa
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基因ID
- 10140
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NCBI登录号
- NM_005749, NP_005740
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UniProt
- P50616
抗原
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