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Protein Tob1 (TOB1) (Middle Region) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 Saccharomyces cerevisiae.
产品编号 ABIN2784777
发货至: 中国

Quick Overview for Protein Tob1 (TOB1) (Middle Region) 抗体 (ABIN2784777)

抗原

See all Protein Tob1 (TOB1) 抗体
Protein Tob1 (TOB1)

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT

    预测反应

    Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 92%, Yeast: 100%

    产品特性

    This is a rabbit polyclonal antibody against TOB1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TOB1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 345 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Protein Tob1 (TOB1)

    别名

    TOB1

    背景

    This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
    Alias Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
    Protein Interaction Partner: CORO7, APP, DTL, CDC7, PABPC1, CHAF1A, PAN2, UBR5, ELAVL1, SMAD3, CTNNB1, UBC, SKP2, SCMH1, MARCKS, SETDB1, CNOT7, SMAD9, SMAD5, SMAD6, SMAD1, SMAD2, SMAD4, MAPK1, ERBB2, RPS6KA1, MAPK9,
    Protein Size: 345

    分子量

    38 kDa

    基因ID

    10140

    NCBI登录号

    NM_005749, NP_005740

    UniProt

    P50616
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